The departures of chief product officer Chris Cox and WhatsApp vice president Chris Daniels were announced Thursday.
"This is an important change as we begin the next chapter of our work building the privacy-focused social foundation of the future," Facebook CEO Mark Zuckerberg wrote in a statement.
"I'm deeply grateful for everything Chris Cox and Chris Daniels have done here, and I'm looking forward to working with Will [Cathcart] and Fidji [Simo] in their new roles as well as everyone who will be critical to achieving this vision."
But after 2016, we both realized we had too much important work to do to improve our products for society, and he stayed to help us work through these issues and help us chart a course for our family of apps going forward," Zuckerberg wrote.
"As Mark has outlined, we are turning a new page in our product direction," Cox wrote in a statement.